| 发明名称 |
Helper virus-free AAV production |
| 摘要 |
A method for the production of adeno-associated virus stocks and recombinant adeno-associated virus stocks that are substantially free of contaminating helper virus is described. The method utilizes transfection with helper virus vectors to replace the infection with helper virus used in the conventional method.
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| 申请公布号 |
US7439065(B2) |
申请公布日期 |
2008.10.21 |
| 申请号 |
US20050208901 |
申请日期 |
2005.08.22 |
| 申请人 |
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL |
发明人 |
FERRARI FORREST K.;XIAO XIAO;SAMULSKI RICHARD JUDE |
| 分类号 |
C12N15/63;A61K48/00;C07K14/075;C12N5/08;C12N5/10;C12N7/01;C12N15/64;C12N15/86;C12N15/861;C12N15/864 |
主分类号 |
C12N15/63 |
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