发明名称 |
COMPOSITIONS AND METHODS FOR TREATING CANCER WITH DACARBAZINE NANOEMULSIONS |
摘要 |
A uniform microfluidized nanoemulsion is disclosed containing an anti-cancer agent, such as dacarbazine. The microfluidized nanoemulsion improves the combination's cell membrane permeability by at least four-fold over conventional nanoemulsion compositions, which significantly increases the intracellular concentration of anti-cancer agents. As a nanoemulsion, dacarbazine has a greater anti-cancer efficacy than when applied as a free solution. |
申请公布号 |
WO2008016664(A3) |
申请公布日期 |
2008.10.16 |
申请号 |
WO2007US17228 |
申请日期 |
2007.08.02 |
申请人 |
UNIVERSITY OF MASSACHUSETTS LOWELL;NICOLOSI, ROBERT;TAGNE, JEAN-BOSCO |
发明人 |
NICOLOSI, ROBERT;TAGNE, JEAN-BOSCO |
分类号 |
A61K9/66 |
主分类号 |
A61K9/66 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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