发明名称 NON-INVASIVE OPTICAL ANALYSIS USING SURFACE ENHANCED RAMAN SPECTROSCOPY
摘要 In one aspect, a system (70) for use in product packaging is disclosed that includes a polymeric sensing substrate (74) coupled to a package (72) such that a front sensing surface (74a) thereof is in contact with a portion of a product, e.g., a fungible product, stored in the package (72) and a back surface (74c) thereof is accessible via an environment external to the package (72). The system further includes a radiation source (80) adapted to direct radiation to the substrate's back surface (74c) such that the radiation would interact with one or more molecular species of the product that are in contact with the substrate's sensing surface (74a). The system also includes a detector (92) that is adapted to detect radiation returning from the substrate in response to its illumination by the radiation source (80).. Thereby, surface enhanced, Raman spectrum (SERS) is obtained. The front surface of the sensing substrate /74a) can comprise a plurality of micron-sized or submicron-sized ridges (74b) having a discontinuous or continuous metal coating, e.g., a metallic layer with a thickness in a range of about 10 nm to^ about 1000 nm (and. preferably in a range of about 50 nm to about 120 nm), disposed thereon.
申请公布号 WO2008091858(A3) 申请公布日期 2008.10.16
申请号 WO2008US51643 申请日期 2008.01.22
申请人 PRESIDENT & FELLOWS OF HARVARD COLLEGE;MAZUR, ERIC;DIEBOLD, ERIC 发明人 MAZUR, ERIC;DIEBOLD, ERIC
分类号 G01N21/65;B65D79/02;G09F3/02 主分类号 G01N21/65
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