发明名称 |
ПИПЕРИДИНОВОЕ ПРОИЗВОДНОЕ ИЛИ ЕГО ФАРМАЦЕВТИЧЕСКИПРИЕМЛЕМАЯ СОЛЬ |
摘要 |
The piperidine derivative of the present invention in which the 4-position of the piperidine ring is bonded, via vinylene, to a mono-substituted (-R 1 ) or unsubstituted benzene ring and the 1-position of the piperidine ring has an acyl group [-C(=O)-R 4 ], or a pharmaceutically acceptable salt thereof has an excellent sodium channel inhibition action and an excellent analgesic action and shows a high analgesic effect particularly to neurogenic pain. The present compound is useful as a sodium channel inhibitor of low side effect |
申请公布号 |
RU2007111957(A) |
申请公布日期 |
2008.10.10 |
申请号 |
RU20070111957 |
申请日期 |
2005.08.31 |
申请人 |
АСТЕЛЛАС ФАРМА ИНК. (JP);КОТОБУКИ ФАРМАСЬЮТИКАЛ КО., ЛТД. (JP) |
发明人 |
КИКУТИ Казуми (JP);ФУДЗИЯСУ Дзиро (JP);ВАТАНАБЕ Тосихиро (JP);НАГАКУРА Юкинори (JP);ТОМИЯМА Хироси (JP);СОНЕГАВА Мотохару (JP);ТОКУЗАКИ Казуо (JP);ИВАИ Йосинори (JP) |
分类号 |
C07D211/16;A61K31/4545;A61K31/496;A61P25/04;C07D401/12;C07D413/06;C07D471/18;C07D487/08 |
主分类号 |
C07D211/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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