PICOLINAMIDE COMPOUND

摘要

Disclosed is a picolinamide compound represented by the formula (1) [wherein R<SUP>1</SUP> represents a C<SUB>1-8</SUB> alkyl group, a C<SUB>1-9</SUB> heteroaryl group, a C<SUB>2-9</SUB> heterocyclyl group or the like; R<SUP>2</SUP> represents a hydrogen atom, a C<SUB>1-8</SUB> alkyl group, a phenyl group, a C<SUB>7-14</SUB> arylalkyl group, or the like; and Ar represents a C<SUB>1-9</SUB> heteroaryl group having a C=N bond wherein a nitrogen atom in an amide group adjacent to the group Ar in the formula (1) is bound to a carbon atom which is a component of the C=N bond in the group Ar]. The picolinamide compound has a GK-activating activity, and is therefore useful as a medicinal agent.