Amino-substituted heterocycles, compositions thereof, and methods of treatment therewith

摘要

Provided herein are Heterocyclic Compounds having the following structure: wherein R¹, R², X, Y and Z are as defined herein, compositions comprising an effective amount of a Heterocyclic Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heterocyclic Compound to a patient in need thereof.