发明名称 Targeting viruses using a modified sindbis glycoprotein
摘要 The present invention relates to viruses that are engineered to contain a surface ligand molecule which targets the virus to a cell of interest. In particular non-limiting embodiments, the cell of interest is desirably ablated and may be a cancer cell, an infected cell, a cell exhibiting a non-malignant proliferative disorder, or a cell of the immune system. Alternatively, the cell of interest is a target for gene therapy.
申请公布号 US7429481(B2) 申请公布日期 2008.09.30
申请号 US20050227778 申请日期 2005.09.14
申请人 UNIVERSITY OF PITTSBURGH 发明人 BERGMAN IRA;WHITAKER-DOWLING PATRICIA
分类号 C12N15/00 主分类号 C12N15/00
代理机构 代理人
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