| 发明名称 |
4-Amino-2,3-disubstituted thieno[2,3-d]pyrimidines and pharmacetical compositions thereof |
| 摘要 |
Furo- and thienopyrimidine derivatives, which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includes methods of making such furo- and thienopyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
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| 申请公布号 |
US7427623(B2) |
申请公布日期 |
2008.09.23 |
| 申请号 |
US20040489052 |
申请日期 |
2004.03.09 |
| 申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
ADAMS JERRY LEROY;BRYAN DEBORAH LYNNE;FENG YANHONG;MATSUNAGA SHINICHIRO;MAEDA YUTAKA;MIYAZAKI YASUSHI;NAKANO MASATO;ROCHER JEAN-PHILIPPE;SATO HIDEYUKI;SEMONES MARCUS;SILVA DOMINGOS J.;TANG JUN |
| 分类号 |
A61K31/519;C07D491/048;A61K31/5377;A61K45/00;A61P1/16;A61P3/10;A61P7/02;A61P9/00;A61P9/10;A61P13/12;A61P17/02;A61P17/06;A61P19/02;A61P25/28;A61P29/00;A61P35/00;A61P37/06;A61P43/00;C07D491/04;C07D495/04;C07D519/00 |
主分类号 |
A61K31/519 |
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