发明名称 Cardio myopeptidin, the production and the use thereof
摘要 The present invention relates to a cardio myopeptidin which is isolated from the hearts of non-human healthy mammals. The molecular weight of the cardio myopeptidin is less than 10000 Dalton, the peptide content thereof being 75%~90%, the free amino acid content 6%~15%, the ribonucleic acid content less than 2%, and the deoxyribonucleic acid content less than 7.5%. The present invention further provides a method of producing the cardio myopeptidin and the use thereof in producing pharmaceuticals for treating cardiac disorders, specifically the use in producing pharmaceuticals for treating myocardial ischemic and reperfusion injury. The cardio myopeptidin of the present invention can work directly on myocytes, promoting the repair of injuries caused by various reasons, and providing a new way to relieve ischemic and reperfusion injury, and to promote the repair of injured myocardium.
申请公布号 US7427663(B2) 申请公布日期 2008.09.23
申请号 US20040567286 申请日期 2004.02.23
申请人 DALIAN ZHEN-AO PHARMACEUTICAL CO., LTD. 发明人 CHEN YUSONG;LI SHU
分类号 C07K14/00;C07K2/00;C07K14/47 主分类号 C07K14/00
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