COMPOSITIONS AND METHODS FOR TREATING DISEASES, DISORDERS OR CONDITIONS CHARACTERIZED BY MYELIN DEGENERATION, MYELIN DEFICIENCY OR LOSS

摘要

Provided herein are novel polypeptides, polynucleotides and compositions containing such, and to methods useful in treating diseases, disorders, or conditions of the central nervous system (CNS) associated with demyelination. The novel polypeptides, polynucleotides stimulate oligodendrocyte precursor cell (OPC), and are capable of promoting myelination or remyelination in a subject.