| 发明名称 |
Monoclonal Antibodies Against The Interferon Receptor, With Neutralizing Activity Against Type I Interferon |
| 摘要 |
The invention relates to a monoclonal antibody directed against the human interferon class I receptor (IFN-R) characterized by the following properties: it recognizes the extracellular domain of the human IFN-R, and it has a neutralizing capacity against the biological properties of the human type I-IFN. It further concerns their use for the diagnosis.
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| 申请公布号 |
US2008226647(A1) |
申请公布日期 |
2008.09.18 |
| 申请号 |
US20080118010 |
申请日期 |
2008.05.09 |
| 申请人 |
MEDAREX, INC. |
发明人 |
BENOIT PATRICK;MEYER FRANCOIS;MAGUIRE DEBORAH;PLAVEC IVAN;TOVEY MICHAEL G. |
| 分类号 |
A61K39/395;G01N33/53;A61K38/00;A61K39/00;A61K39/42;A61P31/00;A61P31/12;A61P37/06;C07K14/52;C07K14/555;C07K14/56;C07K14/565;C07K14/705;C07K14/715;C07K16/00;C07K16/24;C07K16/28;C12N5/02;C12N5/10;C12N5/20;C12N15/02;C12N15/06;C12P21/08;G01N33/577 |
主分类号 |
A61K39/395 |
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