发明名称 PHARMACEUTICAL COMPOUNDS
摘要 The invention provides a composition comprising (S) 2-amino-1-(4-chloro-phenyl)- 1-[4-(1H-pyrazol-4-yl)-phenyl]-ethanol, wherein the composition is either substantially free of (R) 2-amino-1-(4-chloro-phenyl)-1-[4-(1H-pyrazol-4-yl)- phenyl]-ethanol or the composition contains a mixture of the (S) and (R) enantiomers in which the (S) enantiomer predominates. Also provided are processes for the preparation of the (S) 2-amino-1-(4-chloro-phenyl)-1-[4-(1H- pyrazol-4-yl)-phenyl]-ethanol, novel process intermediates and methods for making the novel process intermediates.
申请公布号 WO2008110846(A2) 申请公布日期 2008.09.18
申请号 WO2008GB50180 申请日期 2008.03.14
申请人 ASTEX THERAPEUTICS LIMITED;THE INSTITUTE OF CANCER RESEARCH:ROYAL CANCER HOSPITAL;CANCER RESEARCH TECHNOLOGY LIMITED;ASTRAZENECA AB;WOODHEAD, STEVEN JOHN;REES, DAVID CHARLES;FREDERICKSON, MARTYN;GRIMSHAW, KYLA MERRIOM 发明人 WOODHEAD, STEVEN JOHN;REES, DAVID CHARLES;FREDERICKSON, MARTYN;GRIMSHAW, KYLA MERRIOM
分类号 A61K31/415;A61P35/00;C07D231/12;C07D301/00 主分类号 A61K31/415
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