The present application relates to K-ras mutations, to polynucleotides encoding mutant K-ras polypeptides, and to methods of identifying K-ras mutations. The present application also relates to methods of diagnosing cancer; and methods and kits for predicting the usefulness of anti-EGFr specific binding agents in the treatment of tumors.
申请公布号
WO2008112269(A2)
申请公布日期
2008.09.18
申请号
WO2008US03312
申请日期
2008.03.11
申请人
AMGEN INC.;FREEMAN, DANIEL;JUAN, TODD;RADINSKY, ROBERT