发明名称 |
Enhancement of immune response using targeting molecules |
摘要 |
The present invention provides methods of enhancing the immune response to an immunogen and to compositions for use in these methods. In particular the present invention provides a DNA molecule for use in raising an immune response to an antigen. The DNA molecule includes a first sequence encoding a targeting molecule, a second sequence encoding the antigen or an epitope thereof, and optionally a third sequence encoding a polypeptide which promotes dimerization or multimerization of the product encoded by the DNA molecule.
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申请公布号 |
US7423023(B2) |
申请公布日期 |
2008.09.09 |
申请号 |
US20020185799 |
申请日期 |
2002.06.28 |
申请人 |
CSL, LIMITED |
发明人 |
BOYLE JEFFREY STEPHEN;BRADY JAMIE LOUISE;LEW ANDREW MARK |
分类号 |
A61K31/713;C12N15/09;A61K38/00;A61K39/008;A61K39/015;A61K39/05;A61K39/145;A61K39/385;A61K48/00;A61P31/00;A61P37/04;C07K14/11;C07K14/34;C07K14/435;C07K14/44;C07K14/445;C07K14/47;C07K14/705;C07K16/28;C07K19/00 |
主分类号 |
A61K31/713 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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