| 摘要 |
Disclosed is an antitussive agent which is applicable to the treatment or prevention of cough. The antitussive agent comprises, as an active ingredient, a specific morphinan derivative having a nitrogenated cyclic substituent such as [N-(17-cyclopropylmethyl-4,5alpha-epoxy-3,14-dihydroxy- morphinan-6beta-yl)-3,4,5,6-tetarhydrophthalimide] shown by the formula below or a pharmacologically acceptable acid addition salt thereof. The antitussive agent has an excellent therapeutic or prophylactic effect on cough and produces little adverse side effects.
|
