摘要 |
The invention relates to in vivo imaging agents, specifically radiolabelled insulin derivatives of formula (III); wherein X is -CO-NH-, -NH-, -O-, -NHCONH-, or -NHCSNH-, and is preferably -CO-NH-, -NH- or -O-; Y is H, alkyl or aryl substituents; R* is a radiolabel moiety suitable for detection by SPECT or PET; and methods for preparing the same as well as their use in in vivo imaging methods.
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