发明名称 |
QUINAZOLIN-4-YL- PIPERIDINE AND CINNOLIN-4-YL- PIPERIDINE DERIVATIVES AS PDE10 INHIBITORS FOR THE TREATMENT OF CNS DISORDERS. |
摘要 |
<p>The invention pertains to new piperidyl-substituted quinazoline and isoqu inoline derivatives of formula (I) that serve as effective phosphodiesterase (PDE) inhibitors. The invention also relates to compounds that are selective inhibitors of PDE10. The invention further relates to intermediates for preparation of such compounds; pharmaceutical compositions comprising such compounds; and the use of such compounds in methods for treating certain central nervous system (CNS) or other disorders.</p> |
申请公布号 |
MX2007000878(A) |
申请公布日期 |
2007.03.12 |
申请号 |
MX20070000878 |
申请日期 |
2005.07.11 |
申请人 |
PFIZER PRODUCTS INC. |
发明人 |
LIRAS, SPIROS;CHAPPIE, THOMAS, ALLEN;HUMPHREY, JOHN, MICHAEL |
分类号 |
C07D401/04;C07D401/14;C07D413/14;C07D491/04 |
主分类号 |
C07D401/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|