| 发明名称 |
Use of a metabotropic glutamate receptor 5 antagonist for the treatment of gastro-esphageal reflux disease |
| 摘要 |
The disclosure relates to the use of metabotropic glutamate receptor 5 (mGluR5) antagonists for the inhibition of transient lower esophageal sphincter relaxations (TLESRs). These metabotropic glutamate receptor 5 antagonists are also suitable for the treatment of gastro-esophageal reflux disease (GERD), as well as for the treatment of regurgitation and asthma.
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| 申请公布号 |
NZ536559(A) |
申请公布日期 |
2007.08.31 |
| 申请号 |
NZ20030536559 |
申请日期 |
2003.06.19 |
| 申请人 |
NPS PHARMACEUTICALS, INC;ASTRAZENECA AB |
发明人 |
LEHMANN, ANDERS;MATTSSON, JAN |
| 分类号 |
A61K31/44;A61K;A61K31/4439;A61K45/00;A61P1/04;(IPC1-7):A61K31/44;A61K31/443 |
主分类号 |
A61K31/44 |
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