| 发明名称 |
CHIRAL ARYLKETONES IN THE TREATEMENT OF NEUTROPHIL-DEPENDENT INFLAMMATORY DESEASES |
| 摘要 |
<p>The compounds of formula (I): where Ar is an aromatic ring and Ra, Rb, are as defined in the description, are useful in therapy as drugs for the treatment of diseases mediated by infiltrations of neutrophils induced by IL-8, such as psoriasis, rheumatoid arthritis, ulcerative cholitis and for the treatment of damages caused by ischemia and reperfusion.</p> |
| 申请公布号 |
EP1581474(B1) |
申请公布日期 |
2008.08.27 |
| 申请号 |
EP20030782344 |
申请日期 |
2003.12.09 |
| 申请人 |
DOMPE S.P.A. |
发明人 |
ALLEGRETTI, MARCELLO;BERTINI, RICCARDO;CESTA, MARIA, CANDIDA;BIZZARRI, CINZIA;COLOTTA, FRANCESCO |
| 分类号 |
C07C69/612;A61K31/222;A61P29/00;C07C45/56;C07C45/67;C07C49/213;C07C49/215;C07C49/782;C07C49/784;C07C69/738;C07C69/78;C07C271/18;C07C309/65;C07C311/21;C07C317/06;C07C317/24;C07D209/46;C07D213/50;C07D319/06;C07F9/40 |
主分类号 |
C07C69/612 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
