Process for the preparation of (2r,3s)-3-phenylisoserine methyl ester acetate salt

摘要

A process for the enantioselective preparation of (2 R ,3 S )-3-phenylisoserine methyl ester acetate salt of formula (I)
which is an useful building block for the synthesis of taxane derivatives. The process involves the resolution of racemic threo-phenylisoserine amide and its conversion into (I).