发明名称 Polymorphic and amorphous forms of the phosphate salt of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-CD]indol-6-one
摘要 The present invention relates to novel polymorphic and amorphous forms of a phosphate salt of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one, and to processes for their preparation. Such polymorphic forms may be a component of a pharmaceutical composition and may be used to treat a mammalian disease condition mediated by poly(ADP-ribose) polymerase activity including the disease condition such as cancer.
申请公布号 ZA200701404(B) 申请公布日期 2008.08.27
申请号 ZA20070001404 申请日期 2007.02.16
申请人 PFIZER INC, CANCER RESEARCH TECHNOLOGY LTD. 发明人 LIU, JIA;GUO, MING;BORER, BENNETT, CHAPLIN;MITCHELL, MARK BRYAN;CHU, JAN-JON;NAYYAR, NARESH;WU, ZHEN-PING;SPIRANGAM, APARNA, NADIG;LI, YI.
分类号 A61K;A61P;C07D 主分类号 A61K
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