发明名称 |
Polymorphic and amorphous forms of the phosphate salt of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-CD]indol-6-one |
摘要 |
The present invention relates to novel polymorphic and amorphous forms of a phosphate salt of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one, and to processes for their preparation. Such polymorphic forms may be a component of a pharmaceutical composition and may be used to treat a mammalian disease condition mediated by poly(ADP-ribose) polymerase activity including the disease condition such as cancer. |
申请公布号 |
ZA200701404(B) |
申请公布日期 |
2008.08.27 |
申请号 |
ZA20070001404 |
申请日期 |
2007.02.16 |
申请人 |
PFIZER INC, CANCER RESEARCH TECHNOLOGY LTD. |
发明人 |
LIU, JIA;GUO, MING;BORER, BENNETT, CHAPLIN;MITCHELL, MARK BRYAN;CHU, JAN-JON;NAYYAR, NARESH;WU, ZHEN-PING;SPIRANGAM, APARNA, NADIG;LI, YI. |
分类号 |
A61K;A61P;C07D |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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