Solid pharmaceutical and vaccine dose for parenteral injection

摘要

A solid elongate drug formulation for needle-free parenteral administration at low velocity is disclosed. The solid formulation comprises at least one pointed end comprising at least on active material, and is characterised in that the formulation has a compressive strength of greater than or equal to 5 Newton, and that the pointed end has an included angle of between 10{ and 50{. The needle-less formulation may comprise one or more antigenic or immunogenic agents and may be used as a solid vaccine formulation to vaccinate a vertebrate from infection. Devices using the solid elongate drug formulations are also disclosed, along with methods of making and packaging the formulations. Methods of treatment using the aforementioned drug formulations are also claimed.