发明名称 AMINOBENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION
摘要 FIELD: chemistry. ^ SUBSTANCE: invention relates to aminobenzimidazole and their pharmaceutical compositions having inhibitor potency towards respiratory syncytial virus replication. Aminobenzimidazole is of formula (I) where Q represents Ar2, C3-7cyclalkyl or substituted C1-6alkyl; G represents methylen; R1 represents optionally substituted pyridile; one of R2a and R3a represents C1-6alkyl, and other from R2a and R3a represents hydrogen, in the case if R2a differs from hydrogen R2b represents hydrogen or C1-6alkyl, and R3b represents hydrogen if R3a differs from hydrogen or C1-6alkyl, and R2b represents hydrogen, or all R2a, R2b, R3a and R3b represent hydrogen; R5 represents hydrogen; Ar2 represents optionally substituted phenyl. ^ EFFECT: production of the new biologically active compounds on basis of aminobenzimidazole. ^ 2 cl, 7 ex, 3 tbl
申请公布号 RU2332414(C2) 申请公布日期 2008.08.27
申请号 RU20060125729 申请日期 2004.12.20
申请人 TIBOTEK FARMAS'JUTIKALZ LTD. 发明人 BONFANTI ZHAN-FRANSUA;ANDRIS KUNRAD JOZEF LODEVEJK;JANSSENS FRANS EHDUARD;SOMMEN FRANSUA MARIJA;GIJEMON ZHEROM EHMIL' ZHORZH;LAKRAMP ZHAN FERNAN ARMAN
分类号 C07D401/06;A61K31/4184;C07D401/14;C07D405/14 主分类号 C07D401/06
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