MECHANICALLY INDUCED TRAPPING OF MOLECULAR INTERACTIONS
摘要
The invention provides devices and methods for surface patterning the substrate of a microfluidic device, and for detection and analysis of interactions between molecules by mechanically trapping a molecular complex while substantially expelling solvent and unbound solute molecules. Examples of molecular complexes include protein-protein complexes and protein-nucleic acid complexes.
申请公布号
WO2007089587(A3)
申请公布日期
2008.08.21
申请号
WO2007US02176
申请日期
2007.01.26
申请人
CALIFORNIA INSTITUTE OF TECHNOLOGY;MAERKL, SEBASTIAN, J.;QUAKE, STEPHEN, R.