发明名称 Derivatives of squaric acid with anti-proliferative activity
摘要 The present invention provides derivatives of squaric acid, in particular derivatives of 3,4-diamino-cyclobut-3-ene-1,2-dione and tautomers and isomers thereof, as a single stereoisomer or a mixture of stereoisomers, or as a pharmaceutically acceptable salt thereof. These compounds show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer.
申请公布号 US2008200523(A1) 申请公布日期 2008.08.21
申请号 US20070708793 申请日期 2007.02.21
申请人 MURTHI KRISHNA K;KOSTLER ROLAND;SMITH CHASE;BRANDSTETTER TILMAN;KLUGE ARTHUR F 发明人 MURTHI KRISHNA K.;KOSTLER ROLAND;SMITH CHASE;BRANDSTETTER TILMAN;KLUGE ARTHUR F.
分类号 A61K31/44;A61P35/00;C07D213/74;C12N5/00 主分类号 A61K31/44
代理机构 代理人
主权项
地址