METHOD FOR FORMATION OF TUBULES

摘要

There is provided a method for forming tubules. The method involves providing a gel body enclosing one or more channels with each channel enclosed entirely within the gel body, the gel body comprising basement membrane components and growth medium. A suspension of cells, for example endothelial cells or epithelial cells, is introduced to one or more of the channels and the gel body containing the introduced cells is incubated under conditions sufficient to permit formation of a tubule, the tubule having an interior lumen.