发明名称 4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepine derivatives
摘要 The invention relates to 4-oxo-2,3,4,5-tetrahydro-benzo [b][1,4]diazepines of formula I wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3 </SUP>and R<SUP>4 </SUP>are as defined in the description and claims, which are gamma-secretase inhibitors and which may be useful in the treatment of Alzheimer's disease.
申请公布号 US7414049(B2) 申请公布日期 2008.08.19
申请号 US20070855262 申请日期 2007.09.14
申请人 HOFFMANN-LA ROCHE INC. 发明人 FLOHR ALEXANDER;JAKOB-ROETNE ROLAND;WOSTL WOLFGANG
分类号 A61K31/5513;C07D243/12 主分类号 A61K31/5513
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