发明名称 |
Screening system for identifying drug-drug interactions and methods of use thereof |
摘要 |
The invention features a method of screening for drug-drug interactions using combinational arrays. The method includes the steps of: (a) receiving a test drug from a client; (b) contacting the test drug and at least 200 library drugs from a drug library in an assay under conditions that ensure that each test drug/library drug contacting is segregated from the others; (c) recording the result of the contacting step (b); (d) identifying combinations of drugs that produce a result in the assay that is different from the results produced by either drug of the combination by itself, wherein each identified combination indicates an interaction between the test drug and the library drug of the combination; and (e) communicating the results of the identifying step (d) to the client.
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申请公布号 |
US2008194421(A1) |
申请公布日期 |
2008.08.14 |
申请号 |
US20080011051 |
申请日期 |
2008.01.24 |
申请人 |
BORISY ALEXIS;GRAU DANIEL;STOCKWELL BRENT R;KEITH CURTIS |
发明人 |
BORISY ALEXIS;GRAU DANIEL;STOCKWELL BRENT R.;KEITH CURTIS |
分类号 |
C40B30/06;G01N33/15;C12Q1/02;C12Q1/68;C40B30/00;C40B30/04;G01N33/50;G01N33/68;G01N33/94 |
主分类号 |
C40B30/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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