发明名称 |
Responsive Mri Contrast Agents |
摘要 |
The invention provides MRI contrast agents which provide a high sensitivity and which have an optimised body retention time. These agents enable the mapping of the local pH, temperature, oxygen concentration or other metabolites in a patient's body by the use of Chemical Exchange Saturation Transfer (CEST). Particularly pH and temperature mapping are useful for the detection of small cancer lesions and localised inflammation respectively.
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申请公布号 |
US2008193384(A1) |
申请公布日期 |
2008.08.14 |
申请号 |
US20060912694 |
申请日期 |
2006.04.21 |
申请人 |
KONINKLIJKE PHILIPS ELECTRONICS, N.V. |
发明人 |
WILLARD NICOLAAS PETRUS;WEGH RENE THEODORUS;PIKKEMAAT JEROEN ALPHONS;GRUELL HOLGER |
分类号 |
A61K49/10;C07D403/14 |
主分类号 |
A61K49/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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