发明名称 3-AMINO-PYRROLO[3,4-C] PYRAZOLE- 5 (1H, 4H, 6H) CARBALDEHYDEDERIVATIVES AS PKC INHIBITORS
摘要 The present invention relates to compounds and pharmaceutically acceptabl e salts of Formulas A and B: (A) and (B) wherein A, B, R1, R2, R3, R4, R5, R 6, R7, R8, R9 and R10 are as defined above. The invention further relates to pharmaceutical compositions comprising the compounds and pharmaceutically a cceptable salts and to methods of treating diabetes mellitus and its complic ations, cancer, ischemia, inflammation, central nervous system disorders, ca rdiovascular disease, Alzheimer's disease and dermatological disase pression , virus diseases, inflammatory disorders, or diseases in which the liver is a target organ.
申请公布号 CA2677572(A1) 申请公布日期 2008.08.14
申请号 CA20082677572 申请日期 2008.02.04
申请人 PFIZER INC. 发明人 LI, HUI;YIN, CHUNFENG;SCALES, STEPHANIE ANNE;TENG, MIN;NUKUI, SEIJI
分类号 C07D487/04;A61K31/4162;A61P3/00 主分类号 C07D487/04
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