发明名称 |
NEW COMPOUNDS, METHODS FOR THEIR PREPARATION AND USE THEREOF |
摘要 |
A compound of formula (I) wherein X is CH=CH, CH 2O wherein the oxygen at om is bound to ring B or OCH 2wherein the oxygen atom is bound to ring A; Y is hydrogen, straight or branched C1-C6 alkyl or a pharmaceutically acceptab le inorganic cation; R1 is ethyl or cyclopropyl; and R2 and R3 are the same or different and are selected from F, Cl, Br, CF 3and OCF 3. The compound is useful for the treatment of autoimmune diseases, inflammatory diseases, org an transplant rejection and malignant neoplasia. A pharmaceutical compositio n. A method for preparing the compound.
|
申请公布号 |
CA2677457(A1) |
申请公布日期 |
2008.08.14 |
申请号 |
CA20082677457 |
申请日期 |
2008.01.31 |
申请人 |
CHELSEA THERAPEUTICS, INC. |
发明人 |
VELLMAR, ULF;TUVESSON ANDERSSON, HELEN;SVENSSON, LEIF;FRITZSON, INGELA;HALLIN, INGRID |
分类号 |
C07C233/54;A61K31/196;A61K31/245;A61P29/00;C07C233/63 |
主分类号 |
C07C233/54 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|