Embodiments of the present invention are directed to an optical sensor capable of measuring two analytes simultaneously with a single indicator system. In preferred embodiments, the sensor comprises a fluorescent dye having acid and base forms that facilitate ratiometric pH sensing, wherein the dye is further associated with a glucose binding moiety and configured to generate a signal that varies in intensity with the concentration of glucose.
申请公布号
WO2008097747(A1)
申请公布日期
2008.08.14
申请号
WO2008US52204
申请日期
2008.01.28
申请人
GLUMETRICS, INC.;MARKLE, DAVID, R.;SURI, JEFF, T.;WESSLING, RITCHIE, A.;ROMEY, MATTHEW, A.
发明人
MARKLE, DAVID, R.;SURI, JEFF, T.;WESSLING, RITCHIE, A.;ROMEY, MATTHEW, A.