| 摘要 |
[PROBLEMS] To provide a process for production of 18F-TAFDG, which can produce of 18F-TAFDG with a high radioactive fluorination yield. [MEANS FOR SOLVING PROBLEMS] A process for production of a compound labeled with radioactive fluorine, comprising the steps of: preparing a reaction solution comprising a [18F]fluoride ion, a phase transfer catalyst, 1, 3, 4, 6-tetra-O-acetyl-2-O-trifluoromethanesulfonyl-beta-D-mannopyranose (which is a labeled precursor compound) and a solvent; and subjecting the reaction solution to a reaction under specified reaction conditions to yield 1, 3, 4, 6-tetra-O-acetyl-2-[18F]fluoro-2-deoxyglucose, wherein the solvent contains water.
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