发明名称 COMPUESTOS DERIVADOS DE IMIDAZOL, TRIAZOL Y/O PIRIDINA; COMPOSICION FARMACEUTICA QUE COMPRENDE A DICHOS COMPUESTOS; Y SU USO PARA TRATAR HIPERTENSION O INSUFICIENCIA CARDIACA.
摘要 The invention is directed to compounds having the formula: wherein: Ar, r, R2-3, X, and R5-7 are as defined in the specification, and pharmaceutically acceptable salts thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. The invention is also directed to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
申请公布号 CL2008001201(A1) 申请公布日期 2008.08.08
申请号 CL20080001201 申请日期 2008.04.24
申请人 THERAVANCE, INC. 发明人 ALLEGRETTI, PAUL, CHOI, SEOK-KI, GENDRON, ROLAND,FATHEREE, PAUL R., JENDZA, KEITH, MCKINNELL, ROBERT MURRAY, MCMURTRIE,
分类号 A61K31/4164;A61K31/44;A61P9/00;C07D213/64;C07D233/90 主分类号 A61K31/4164
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