发明名称 |
COMPUESTOS DERIVADOS DE 6-OXO-6,7-DIHIDRO-5H-DIBENZO-[B,D]AZEPIN-7-ILO; PROCEDIMIENTO DE PREPARACION; COMPOSICION FARMACEUTICA QUE COMPRENDE A DICHO COMPUESTO; Y USO DEL COMPUESTO EN EL TRATAMIENTO DE LA ENFERMEDAD DE ALZHEIMER O CANCER. |
摘要 |
The invention relates to 6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl derivatives of formula I wherein R1, R2 and R3 are as defined herein. The compounds are gamma-secretase inhibitors useful in the treatment of Alzheimer's disease or common cancer, including, but not limited to, cervical carcinomas and breast carcinomas and malignancies of the hematopoietic system. |
申请公布号 |
CL2008000254(A1) |
申请公布日期 |
2008.08.08 |
申请号 |
CL20080000254 |
申请日期 |
2008.01.30 |
申请人 |
F. HOFFMANN-LA ROCHE AG. |
发明人 |
ALEXANDER FLOHR, ROLAND JAKOB-ROETNE Y WOLFGANG WOSTL. |
分类号 |
A61K31/55;A61P25/28;A61P35/00;C07D233/18 |
主分类号 |
A61K31/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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