| 发明名称 |
FUSED AROMATIC DIFLUOROMETHANEPHOSNATES AS PROTEIN TYROSINE PHOSPHATASE 1B ((PTP-1B) INHIBITORS |
| 摘要 |
<p>The invention encompasses the novel class of compounds represented by the formula below, which are inhibitors of the PTP-1B enzyme. The invention als o encompasses pharmaceutical compositions which include the compounds shown (Formula I) above and methods of treating or preventing PTP-1B mediated dise ases, including diabetes.</p> |
| 申请公布号 |
CA2675142(A1) |
申请公布日期 |
2008.07.31 |
| 申请号 |
CA20082675142 |
申请日期 |
2008.01.24 |
| 申请人 |
MERCK FROSST CANADA INC. |
发明人 |
COLUCCI, JOHN;BAYLY, CHRISTOPHER;BELLEY, MICHEL;DUFRESNE, CLAUDE;WILSON, MARIE-CLAIRE;HAN, YONGXIN;LAU, CHEUK K. |
| 分类号 |
C07F9/60;A61K31/662;A61K31/675;A61P3/10;A61P35/00;C07F9/38;C07F9/40 |
主分类号 |
C07F9/60 |
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