发明名称 |
POLYMER-LINKED-BISPHOSPHONATE INHALANT FORMULATIONS AND METHODS FOR USING THE SAME |
摘要 |
<p>The present invention provides for methods of administering a bisphosphonate active agent to a subject in need thereof. Aspects of the invention include administering the bisphosphonate active agent to the subject by a pulmonary route, where the bisphosphonate active agent is bonded, either directly or through an intervening linking group, to a non-peptide polymer, such that the bisphosphonate active agent is a polymer-linked-bisphosphonate active agent. Also provided are compositions for use in practicing methods according to embodiments of the invention. Methods and compositions according to embodiments of the invention find use in a variety of different applications, including but not limited to, the treatment of bone adsorption disease conditions.</p> |
申请公布号 |
WO2008091337(A1) |
申请公布日期 |
2008.07.31 |
申请号 |
WO2007US26427 |
申请日期 |
2007.12.27 |
申请人 |
TEIKOKU PHARMA USA, INC.;KATSUMI, HIDEMASA;YAMAMOTO, AKIRA;NAKATANI, MARIA |
发明人 |
KATSUMI, HIDEMASA;YAMAMOTO, AKIRA;NAKATANI, MARIA |
分类号 |
A61K31/67;A61K31/74;C07D327/00 |
主分类号 |
A61K31/67 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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