| 发明名称 |
SUBSTITUTED PHENYL DERIVATIVES, THEIR PREPARATION AND USE |
| 摘要 |
The present invention discloses compounds having the formula <CHEM> wherein one of R<1>, R<2> and R<3> is a acidic functional group having a pKa value below 8 or a group which is convertible in vivo to such a group; and Y represents <CHEM> wherein R<0> and R<00> independently represents hydrogen or lower alkyl; X represents O or S. <??>The compounds are useful as chloride channel blockers. |
| 申请公布号 |
PL198852(B1) |
申请公布日期 |
2008.07.31 |
| 申请号 |
PL19990347371 |
申请日期 |
1999.10.19 |
| 申请人 |
NEUROSEARCH A/S |
发明人 |
DAHL BJARNE H.;CHRISTOPHERSEN PALLE |
| 分类号 |
C07C275/42;C07D233/34;A61K31/17;A61K31/18;A61K31/192;A61K31/41;A61K31/4166;A61K31/4439;A61K31/496;A61P1/04;A61P1/12;A61P7/06;A61P9/10;A61P9/12;A61P17/02;A61P19/08;A61P19/10;A61P27/06;A61P29/00;A61P35/00;A61P35/04;A61P37/08;A61P43/00;C07C233/64;C07C273/18;C07C275/30;C07C275/32;C07C381/06;C07D233/32;C07D257/04;C07D401/12 |
主分类号 |
C07C275/42 |
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