发明名称 Macrocyclic polymorphs, compositions comprising such polymorphs, and methods of use and manufacture thereof
摘要 The invention relates to a crystalline polymorphic form comprising a compound of formula I, compositions comprising such a crystalline polymorphic form, processes for manufacture and use thereof. The compounds and compositions of the invention are useful in the pharmaceutical industry, for example, in the treatment or prevention of diseases or disorders associated with the use of antibiotics, chemotherapies, or antiviral therapies, including, but not limited to, colitis, for example, pseudo-membranous colitis; antibiotic associated diarrhea; and infections due to Clostridium difficile ("C. difficile"), Clostridium perfringens ("C. perfringens"), Staphylococcus species, for example, methicillin-resistant Staphylococcus, or Enterococcus including Vancomycin-resistant enterococci.
申请公布号 AU2008209580(A1) 申请公布日期 2008.07.31
申请号 AU20080209580 申请日期 2008.01.22
申请人 OPTIMER PHARMACEUTICALS, INC. 发明人 ALEX ROMERO;YOSHI ICHIKAWA;YOUE-KONG SHUE;YU-HUNG CHIU;TESSIE MARY CHE
分类号 C07H17/08;A61K31/7048;A61P31/04 主分类号 C07H17/08
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