发明名称 Pyridine méthylène azolidinones and use thereof phospho-inositide inhibitors
摘要 The present invention relates to pyridine methylene azolidinone compounds of Formula (I) for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, allergy, asthma, pancreatitis, multi-organ failure, kidney diseases, platelet aggregation, cancer, sperm motility, graft rejection or lung injuries. Specifically, the present invention is related to pyridine methylene azolidinone derivatives for the modulation, notably the inhibition of the activity or function of the phosphoinositide-3-kinases, PI3Ks.
申请公布号 ZA200701666(B) 申请公布日期 2008.07.30
申请号 ZA20070001666 申请日期 2005.09.02
申请人 LABORATROIRES SERONO SA. 发明人 RUECKLE, THOMAS;QUATTROPANI, ANNA;POMEL, VINCENT;DORBAIS, JEROME;COVINI, DAVID;BISCHOFF, ALEXANDER
分类号 A61K;C07D 主分类号 A61K
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