发明名称 QUINAZOLINE DERIVATIVES AS ALPHA-1 ADRENERGIC ANTAGONISTS
摘要 This invention relates to compounds which are generally alpha-1B adrenergic receptor antagonists and which are represented by general formula (I) wherein R1, R2, m, n, and A are as defined in the specification, or prodrugs, individual isomers, racemic or non-racemic mixtures of isomers, or pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds, the use of such compounds in the control and prevention of diseases, such as disorders of the urinary tract, sexual dysfunction, pain, or disorders of the central nervous system, and methods of preparation thereof.
申请公布号 CA2420177(C) 申请公布日期 2008.07.08
申请号 CA20012420177 申请日期 2001.08.23
申请人 F. HOFFMANN-LA ROCHE AG 发明人 BECKER, CYRUS KEPHRA;ZHANG, XIAOMING;PFISTER, JUERG ROLAND;MELVILLE, CHRIS RICHARD
分类号 C07D401/12;A61K31/506;A61K31/517;A61P13/02;A61P15/10;A61P25/00;A61P25/04;A61P25/18;A61P25/20;A61P43/00;C07D401/14;C07D405/14 主分类号 C07D401/12
代理机构 代理人
主权项
地址