TRANSDERMAL THERAPEUTIC SYSTEMS HAVING IMPROVED STABILITY AND THEIR PRODUCTION

摘要

The invention relates to a transdermal therapeutic system (TTS). In said system, the formation of oxidative degradation products is reduced by at least one active ingredient which is contained in the system and can be oxidised by hydroperoxides during storage of the TTS. Said system is characterised in that the maximum sum of the peroxide numbers (POZ), exhibited by the constituent parts of the formulation which contain the active ingredient(s) prescribed by the recipe for the TTS is 20. The invention also relates to a method for producing a transdermal therapeutic system of this type.