发明名称 |
Methods and Compositions for the Treatment of Lipid-Associated Disorders |
摘要 |
The invention provides a method of identifying a niacin receptor modulator with reduced flushing effect compared to niacin or a niacin analog, comprising determining the MAP kinase activity of said modulator, wherein a decrease in MAP kinase activity induced by said modulator compared to MAP kinase activity induced by niacin or a niacin analog indicates that said modulator has reduced flushing effect when compared to niacin or a niacin analog.
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申请公布号 |
US2008161422(A1) |
申请公布日期 |
2008.07.03 |
申请号 |
US20060884675 |
申请日期 |
2006.02.18 |
申请人 |
KANEMITSU-PARKS MARTHA;RICHMAN JEREMY G;MACIEJEWSKI-LENOIR DOMINIQUE;CONNOLLY DANIEL T |
发明人 |
KANEMITSU-PARKS MARTHA;RICHMAN JEREMY G.;MACIEJEWSKI-LENOIR DOMINIQUE;CONNOLLY DANIEL T. |
分类号 |
A61K35/00;C12Q1/48;G01N33/566 |
主分类号 |
A61K35/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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