发明名称 |
POWDER FORMATION BY ATMOSPHERIC SPRAY-FREEZE DRYING |
摘要 |
A method of manufacturing heat-sensitive pharmaceutical powder is disclosed. The original pharmaceutical substances are dissolved in a solution or suspended in a suspension, which is sprayed through an atomizing nozzle and frozen in a cold gas phase or liquid nitrogen atomized directly in the spray-freeze chamber or gas jacket at the same time (for cooling purposes). The particles are freeze-dried at roughly atmospheric pressure in a down-stream fluid flow with exit filter thereby to remove moisture entrapped on or inside the frozen particles. The system has applicability for forming other powders.
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申请公布号 |
US2008155853(A1) |
申请公布日期 |
2008.07.03 |
申请号 |
US20080050654 |
申请日期 |
2008.03.18 |
申请人 |
WANG ZHAOLIN;FINLAY WARREN H |
发明人 |
WANG ZHAOLIN;FINLAY WARREN H. |
分类号 |
F26B5/00;A61J3/02;A61K9/14;A61K9/19;B01J2/04;F26B5/06 |
主分类号 |
F26B5/00 |
代理机构 |
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