发明名称 ANTIBODIES AGAINST INSULIN-LIKE GROWTH FACTOR I RECEPTOR ANDUSES THEREOF
摘要 An antibody binding to IGF-IR and being glycosylated with a sugar chain a t Asn297, said antibody being characterized in that the amount of fucose wit hin said sugar chain is between 20% and 50%, has improved properties in anti tumor therapy.
申请公布号 CA2672715(A1) 申请公布日期 2008.07.03
申请号 CA20072672715 申请日期 2007.12.19
申请人 F. HOFFMANN-LA ROCHE AG 发明人 KOLL, HANS;KUENKELE, KLAUS-PETER;MOSER, SAMUEL;POEHLING, SYLKE
分类号 C07K16/28;A61K39/395;A61P35/00;C12N5/12 主分类号 C07K16/28
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