发明名称 |
ANTIBODIES AGAINST INSULIN-LIKE GROWTH FACTOR I RECEPTOR ANDUSES THEREOF |
摘要 |
An antibody binding to IGF-IR and being glycosylated with a sugar chain a t Asn297, said antibody being characterized in that the amount of fucose wit hin said sugar chain is between 20% and 50%, has improved properties in anti tumor therapy.
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申请公布号 |
CA2672715(A1) |
申请公布日期 |
2008.07.03 |
申请号 |
CA20072672715 |
申请日期 |
2007.12.19 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
KOLL, HANS;KUENKELE, KLAUS-PETER;MOSER, SAMUEL;POEHLING, SYLKE |
分类号 |
C07K16/28;A61K39/395;A61P35/00;C12N5/12 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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