发明名称 |
Non-anaphylactic Forms of Grass Pollen Ph1 p 6 Allergen and Their Use |
摘要 |
Methods for desensitization of a mammal suffering from IgE mediated allergy comprise the steps of: administering to said mammal a therapeutically effective amount of an immunogenic and hypoallergenic composition which comprises (i) a Phi p 6 molecule having an N-terminal truncation which makes the molecule at least lack IgE binding capacity, and/or (ii) a Phi p 6 molecule having a C-terminal truncation which makes the molecule at least lack IgE binding capacity, wherein the molecules of (i) and (ii), if employed in combination, together span the complete sequence of Phl p 6, and a pharmaceutically acceptable carrier.
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申请公布号 |
US2008160038(A1) |
申请公布日期 |
2008.07.03 |
申请号 |
US20070933498 |
申请日期 |
2007.11.01 |
申请人 |
VALENTA RUDOLF;VRTALA SUSANNE;STUMVOLL SABINE;GRONLUND HANS;GROTE MONIKA;VANGELISTA LUCA;PASTORE ANNALISA;SPERR WOLFGANG R;VALENT PETER;KRAFT DIETRICH |
发明人 |
VALENTA RUDOLF;VRTALA SUSANNE;STUMVOLL SABINE;GRONLUND HANS;GROTE MONIKA;VANGELISTA LUCA;PASTORE ANNALISA;SPERR WOLFGANG R.;VALENT PETER;KRAFT DIETRICH |
分类号 |
A61K39/35;A61K38/11;A61K39/00;A61K39/36;C07K14/415 |
主分类号 |
A61K39/35 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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