| 发明名称 |
Methods of Screening Compounds Inhibiting Signal Transduction Through Inflammatory Cytokines |
| 摘要 |
Revealed are that the actions of inflammatory cytokine and the production of inflammatory cytokines such as IL-1 and TNF induced by an inflammatory stimulus as well as the production of other inflammatory cytokines such as IL-6 induced by the former class of inflammatory cytokines are all suppressed by inhibiting the signal transduction through TAK1.
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| 申请公布号 |
US2008160541(A1) |
申请公布日期 |
2008.07.03 |
| 申请号 |
US20080026932 |
申请日期 |
2008.02.06 |
| 申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
TSUCHIYA MASAYUKI;OHTOMO TOSHIHIKO;SUGAMATA YASUHIRO;MATSUMOTO KUNIHIRO |
| 分类号 |
G01N33/53;A61K38/00;C07K14/47;C12N9/12;C12Q1/48;G01N33/573 |
主分类号 |
G01N33/53 |
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