| 摘要 |
FIELD: medicine; pharmacology. ^ SUBSTANCE: invention refers to production of medicinal agents for dementia treatment, including Alzheimer's disease (AD), method of treatment and pharmaceutical composition effective for dementia treatment, including AD or Alzheimer's dementias, as well as first signs of memory derangement. Offered invention implies application of polyprenols of formula where n=8-20, as active ingredients for medicinal agent and treatment of dement syndrome and for medicinal agent and treatment of Alzheimer's disease. Offered pharmaceutical composition is used for treatment of dement syndrome, including Alzheimer's disease, and pharmaceutically acceptable adjuvants, including carriers, and/or solvents, additives and/or lubricants. Pharmaceutical composition can be made as solution, suspension, tablets, filmed tablets, capsules, rectal suppositories, liposome form. Pharmaceutical composition is oil solution, parenteral suspension or solid form for oral application, so specified polyprenol content is 0.10 to 80 mass.%. Offered method of treatment applied for dement syndrome, including Alzheimer's disease, is distinguished by the fact that patients are introduced with effective amount of polyprenols of formula where n=8-20, as separate agent or within pharmaceutical composition containing assist ingredients. Agent based on specified composition provides aid for patients suffering from first signs of memory derangement. ^ EFFECT: due to absence of by-effects treatment with polyprenols can be performed within long period of time. ^ 7 cl, 2 tbl, 5 ex |
