IMIDAZOPYRAZINES AS PROTEIN KINASE INHIBITORS

摘要

In its many embodiments, the present invention provides a novel class of imidazopyrazine compounds of following formula (1) as inhibitors of protein and/or Aurora kinases. methods of preparing such compounds, pharmaceutical compositions including one or more such compounds, methods of preparing pharmaceutical formulations including one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the protein or Aurora kinases using such compounds or pharmaceutical compositions, such as cancer and leukemia.