COMPOSITIONS AND METHODS TO TREAT MUSCULAR & CARDIOVASCULAR DISORDERS
摘要
The present invention relates to a novel microRNA, mir-208-2, implicated in muscular and cardiovascular disorders. The present invention also relates to oligonucleotide therapeutic agents (antisense oligonucleotides and/or do uble stranded oligonucleotides such as dsRNA) and their use in the treatment of muscular and cardiovascular disorders resulting from dysregulation of mi r-208-2.
申请公布号
CA2672606(A1)
申请公布日期
2008.06.26
申请号
CA20072672606
申请日期
2007.12.13
申请人
NOVARTIS AG
发明人
HALL, JONATHAN;BEUVINK, IWAN;SERLUCA, FABRIZIO;MUELLER, MATTHIAS;WEILER, JAN;SCHINKE-BRAUN, MARTINA;SCHNELL, CHRISTIAN